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Ganoderma (LINGZHI)

Thousands of years ago in China, Ganoderma has been revered as the "king of Herbs". It ranks number 1 amongst the variety of Chinese healing herbs. With its detoxification/cleansing in the body, restore system balance and helps strengthen immune system and cell integrity.

Ganoderma lucidum is a basidiomycete, lamellaless fungus that belongs to the family of polyporaceae. It is also known as Ling Zhi (Chinese), Reishi (Japanese), King of Herbs or God’s Herb. It grows in densely wooded mountains of high humidity and dim lighting. The Polypores (or those of the polyporaceae family), commonly known as brackets or shelf fungi, are prominent mushrooms that grow off the sides of trees.

“Mushroom” is the fruit body of a mycelial tree and has a high-reproductive structure of higher order fungus organism. On the other hand, a mycelium is a network of the threadlike filaments that originate from spores.One of the characteristics of a pure Reishi is that it has an intensely bitter taste.

In modern times, Reishi has been the object of intensive scientific studies to determine its many health benefits from a modern perspective, as it is believed that it has several other major effects in the human body. In fact, continuing researches on the wonders of Ganoderma are not only confined in the Orient – specifically in China, Korea and Japan – but in other Western countries as well.

Its application has been utilized further not only as a supplement but it is also being applied for pharmaceuticals, cosmetics and beverages

Ancient Beliefs about Ganoderma

Numerous legends provide a rich and extensive account about Ganoderma lucidum. It was said that in the early days in China, Ganoderma is very rare and hard to obtain. People during the time of the emperors considered it as a treasure greater than any jewel because they believe it provides an incredible source of energy and youthfulness. Furthermore, it was also mentioned that

1. It is the favourite food supplement of the Chinese Royal Family

2. Taoist revered it as "Elixir of Immortality,"

3. The Emperors of the Great Chinese dynasties, including Japanese royalties, drank tea and concoctions of mushrooms for vitality and long life.

4. In the first Chinese Herbal Text (Shennong Pharmacopeia) written about 2,400 years ago, Reishi is classified as a “superior herb,” which was defined as one that “promotes radiant health and long life because of its normalizing action, and (it is also believed) to cause no side effects even when use(d) continuously.” Reishi is traditionally called as “the mushroom of immortality.”

5. The late Hiroshi Hikino, recognized as the world’s authority on the chemistry of Oriental medicinal plants, called Reishi as one of “the most important elixir(s) in the orient.”

6. It also increases intellectual capacity and banishes forgetfulness.

7. Presently in Asia, it ranks parallel to Ginseng in terms of potency.

The Magic Effects of Ganoderma

Ganoderma has always been shrouded with a mysterious curtain for more than a thousand years. People only know 'Ganoderma can keep one young than give one a long life if taken continously, but no one had ever scientifically investigated why it is so effective.

Under the attentive research done by both Chinese and foreign scholars in recent years, and the cooperative analysis and clinical experiments done by hospitals, colleges, and pharmaceutical manufacturers, its extensive efficacy has finally discovered. It is a hemocatharsis, detoxicant, diuretic, liver protector, intestine regulator, cardiotonic, blood pressure adjustor, a cold tonic, antitussive and expectorant, a tranquilizer, an anti-tumor drug.

Important Components of Ganoderma

1. Organic Germanium (Ge): This can increase the oxygen absorbed by the blood up to 1.5 times, can promote metabolism, and prevent tissue degeneration. According to the research of Dr. Kazuhiko Asai, Ganoderma contains 800-2000 p.p.m. of germanium. This is 4-6 more than ginseng.

2. Polysaccharides: These can improve the body's immune system, and eliminate viruses. Japanese pharmaceutical companies have refined it to medical quality and it has been approved by Koseisho Health Department in Japan for insurance medicine.

3. Its bitter taste. It is under constant study by the Japanese medical and pharmaceutical fields. The efficacy is a result of the interrelation of germanium and polysaccharides. Some plants may contain one or the other, but Ganoderma is much more effective. The combination of components is different from other plants and all of the components must be preserved to insure efficiency.

Ganoderma lucidum and its pharmaceutically active compounds

Ganoderma lucidum is a wood-degrading basidiomycete with numerous pharmacological effects. Since the mushroom is very rare in nature, artificial cultivation of fruiting bodies has been known on wood logs and on sawdust in plastic bags or bottles. Biotechnological cultivation of G. lucidum mycelia in bioreactors has also been established, both on solid substrates and in liquid media by submerged cultivation of fungal biomass. The most important pharmacologically active constituents of G. lucidum are triterpenoids and polysaccharides. Triterpenoids have been reported to possess hepatoprotective, anti-hypertensive, hypocholesterolemic and anti-histaminic effects, anti-tumor and anti-engiogenic activity, effects on platelet aggregation and complement inhibition. Polysaccharides, especially beta-d-glucans, have been known to possess anti-tumor effects through immunomodulation and anti-angiogenesis. In addition, polysaccharides have a protective effect against free radicals and reduce cell damage caused by mutagens.

source

Ganoderma lucidum spore extract inhibits endothelial and breast cancer cells in vitro.

This study was conducted to investigate the anti-proliferative activities of medicinal mushroom Ganoderma lucidum (Rei-shi or Mannentake). We have identified an alcohol extract from the spore of Ganoderma lucidum that inhibits the in vitro proliferation of human umbilical vein endothelial cells and MDA-MB231 human breast cancer cells. Further fractionation of the alcohol extract revealed that the ethyl acetate fraction inhibited both cell lines in a dose-dependent manner from 2 to 40 micro g/ml. Our results suggest that the alcohol extract from the spore of Ganoderma lucidum may possess potential anti-tumor and anti-angiogenic activities.

source

Ganoderma lucidum (Reishi) in cancer treatment

The popular edible mushroom Ganoderma lucidum (Reishi) has been widely used for the general promotion of health and longevity in Asian countries. The dried powder of Ganoderma lucidum was popular as a cancer chemotherapy agent in ancient China. The authors recently demonstrated that Ganoderma lucidum inhibits constitutively active transcription factors nuclear factor kappa B (NF-kappaB) and AP-1, which resulted in the inhibition of expression of urokinase-type plasminogen activator (uPA) and its receptor uPAR. Ganoderma lucidum also suppressed cell adhesion and cell migration of highly invasive breast and prostate cancer cells, suggesting its potency to reduce tumor invasiveness. Thus, Ganoderma lucidum clearly demonstrates anticancer activity in experiments with cancer cells and has possible therapeutic potential as a dietary supplement for an alternative therapy for breast and prostate cancer. However, because of the availability of Ganoderma lucidum from different sources, it is advisable to test its biologic activity.

source

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DXN Health Food Supplement Series

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Reishi Gano (RG)

Reishi Gano (RG) is a kind of mushroom essence formulated from Ganoderma lucidum. It contains a wide variety of nutrients such as polysaccharides, adenosine, triterpenoids, protein and fibre.
The applied Ganoderma lucidum is harvested from a 90-day old red mushroom. Comes in capsule and powder forms, daily intake of Reishi Gano (RG) helps in normalizing the entire body functions and maintains the healthy well being.

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30, 90 and 360 capsules
- 15g powder/ bottle


Price: RG-30 - PHP 500 pesos
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GL is effective in improving the general health of our body. Like RG, Ganocelium® is also available in both capsule and powder forms.

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- 30, 90 and 360 capsules
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