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Avoid Failures

Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum.

el-Mekkawy S, Meselhy MR, Nakamura N, Tezuka Y, Hattori M, Kakiuchi N, Shimotohno K, Kawahata T, Otake T.

Research Institute for Traditional Sino-Japanese Medicines, Toyama Medical and Pharmaceutical University, Japan.

A new highly oxygenated triterpene named ganoderic acid alpha has been isolated from a methanol extract of the fruiting bodies of Ganoderma lucidum together with twelve known compounds. The structures of the isolated compounds were determined by spectroscopic means including 2D-NMR. Ganoderiol F and ganodermanontriol were found to be active as anti-HIV-1 agents with an inhibitory concentration of 7.8 micrograms ml-1 for both, and ganoderic acid B, ganoderiol B, ganoderic acid C1, 3 beta-5 alpha-dihydroxy-6 beta-methoxyergosta-7,22-diene, ganoderic acid alpha, ganoderic acid H and ganoderiol A were moderately active inhibitors against HIV-1 PR with a 50% inhibitory concentration of 0.17-0.23 mM.

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Some outstanding results obtained recently are simply analyzed below, in order to evaluate the efficacy of Ganoderma

1. Headache and shoulder pain caused by hypertension and arteriosclerosis are completely cured, and blood pressure also improved.
Reported by mr. Isao Tani of the Medical Research Institute of Kinki University.

The experimental subjects were predominantly hypertension patients. Blood pressure showed significant improvement. One patient with reading of 180/96, had a reading of 126/94 after three months. Such remarkable improvement is rarely seen without using antihypersentive medicine.

Some female arteriosclerosis patients' blood pressure dropped to 128/67 from 158/77, within three months. Their cholesterol level also improved from 269 to 242.

Some patients have hypertension with headache and shoulder pain. Their blood pressure dropped form 151/78 to 118/72 in one month, and headaches were eliminated.

Of a number of patients who had blood pressure and pain problems, both conditions improved.

Based on the above results, we may see that Ganoderma is useful to hypertension patients. using anti-hypertensive to lower blood pressure can lower the systolic pressure, but not the diastolic pressure. Ganoderma can lower both. This is its outstanding quality.

2. Why is it effective for both systolic and diastolic pressure?
Dr. Shigere Yuji of Kinki University give six explanations why Ganoderma is effective for cardio-vascular diseases.

a. Treats hypertension.
b. Elevates blood pressure of hypotensive patients.
c. Prevents arteriosclerosis and lowers cholesterol level.
d. Prevents thrombogenesis and dissolves thrombi.
e. Reduces the side effects of antihypertensive.
f. used together with hypertnesive, causes a hypotensive effect.

3. It is also effective in treating cerebral vascular obstruction, cardiac infraction and cerebral apoplexy and angina pectoris.
Reported by Mr. Uebara Kioshi of Kinki University

Taking Ganoderma can reduce the serious symptoms of the above diseases, without traditional treatment. Among these cases, was a patient with a right cerebral arterial obstruction which occured twice. He received the best result after taking Ganoderma and Urokinase, together. Complete mobility finally returned.

A patient suffering from cerebral vascular obstruction, who was partially paralayzed, could move freely after taking Ganoderma. His free fat and B-lipo protein value returned to normal.

Taking Ganoderma together improve the condition of cardiac patients. This proves that taking Ganoderma together with other drugs, may result in better result. By the way, since the above diseases are difficult to cure, it is better to take Ganoderma regularly to prevent their occuring in the first place.

4.It is effective in the treatment of acute or chronic hepatitis, or liver dysfunction.
Reported by Dr. Mitsui Hashimoto of Hashimoto Hospital

At the present time, hepatitis is still a disease, which can not be treated with any specific method. If Ganoderma is effective, it would be a meaningful medicine for its treatment.

Six capsules per day were prescribed to some patients with hepatitis. Three months later, all patients were recoverin, their GOT and GPT values decreased from 200-300 to 100.

In addition, one patient who used Ganoderma together with some Chinese herbal medicines resulted in a decreased GOT and GPT. There was one case of hepatitis combined with hypertension. After taking Ganoderma, satisfactory results were obtained.

The above conditions can not be conclusive, but positive results of taking Ganoderma on hepatitis can be expected.

When liver function is declining, the patient may get tired. Taking Ganoderma can help ease fatigue.

5. The believe that 'Liver disease is incurable' should be abandoned.
The liver is the most important organ for health. Liver function is quite complicated. Therefore, liver diseases are considered difficult to treat, and dietetic treatment is the only method adopted by Westerns physicians.

However, Ganoderma is able to make the complicated organ function and bring it back to normal. Based on our practical investigation. Ganoderma can contribute a very positive effect. Dr. Shigeru Yuji reported that 10% of liver disorders could be cured after taking for two months. 40% of the patients were relieved of their symptoms, and their liver size was reduced. 50% of the patients felt their symptoms diminished.


DISCLAIMER

Despite all the possible health benefits that can be obtained from Ganoderma Lucidum, it is not intended to replace the recommendations of a medical doctor. This product is not sold as a drug but a "Food Supplement". Patients with specific problem should always consult their physician. All health benefit claims are based on reports of researches made by scientists in Japan.

The Japanese medical field has confirmed that Ganoderma has positive efficacy.

Physicians all over the world are concerned about high quality medicines. A new medical term "Adaptogen" has been coined to indicate the specific effects of Ganoderma.

After long term research and experiments done by large Japanese hospitals and research institutues. Ganoderma's positive effects have been confirmed in every respect, especially its hemocatharsis effect, e.e., improves a weak constitution, and enhances the immune system. It has an evident efficacy in treating diseases caused by poor circulation. It is helpful in maintaining healthy and healthy appearance. The Japanese medical field is surprised and has acknowledged its positive effects on the following diseases:

1. hypertension and hypotension
2. cardiac disease originating from hypertension and hematoma
3. cerebral apoplexy, high blood sugar, blood vessel obstruction
4. menopause disturbances, gynecological diseases
5. constipation. hemorrhoids
6. chronic hepatitis
7. urination difficulties, frequent urination
8. gastric diseases, duodenal ulcers
9. hypersensitivity, including nasal sensitivity and chronic catarrh
10. chronic bronchitis, asthma
11. arthritis, lumbago, rheumatism (after middle age)
12. insomnia, lethargy, neurasthenia
13. skin rashes due to hypersensitivity, athlete's foot, and ringworm due to hematoma

It may sound strange that Ganoderma has an inverse effect, i.e., it can both raise and lower blood pressure. Actually, because Ganoderma can harmonize body functions, increasing the natural healing ability of the body, it can strengthen the immune system, especially for the middle aged.

With Ganoderma, some people may experience reactions after beginning treatment. Some may have dizziness, weakness, or itching, or repeated defecation and urination. These are normal phenomena which indicate that the positive effects are beginning, by dissolving the stored toxicants and discharging them. Patients with diabetes may lose a large amount of sugar, patients with rheumatism may have temporary intense pain. These phenomena are purely the normal, functional, adjustments, within the body. It is nothing but the performance of its efficacy. According to one's personal constitution, the reactions will disappear in a few days.

Since Ganoderma is a natural medicine, it can be used with other Western drugs. Not only are there no adverse, it can also reduce the side effects of Western drugs.

Ganoderma (LINGZHI)

Thousands of years ago in China, Ganoderma has been revered as the "king of Herbs". It ranks number 1 amongst the variety of Chinese healing herbs. With its detoxification/cleansing in the body, restore system balance and helps strengthen immune system and cell integrity.

Ganoderma lucidum is a basidiomycete, lamellaless fungus that belongs to the family of polyporaceae. It is also known as Ling Zhi (Chinese), Reishi (Japanese), King of Herbs or God’s Herb. It grows in densely wooded mountains of high humidity and dim lighting. The Polypores (or those of the polyporaceae family), commonly known as brackets or shelf fungi, are prominent mushrooms that grow off the sides of trees.

“Mushroom” is the fruit body of a mycelial tree and has a high-reproductive structure of higher order fungus organism. On the other hand, a mycelium is a network of the threadlike filaments that originate from spores.One of the characteristics of a pure Reishi is that it has an intensely bitter taste.

In modern times, Reishi has been the object of intensive scientific studies to determine its many health benefits from a modern perspective, as it is believed that it has several other major effects in the human body. In fact, continuing researches on the wonders of Ganoderma are not only confined in the Orient – specifically in China, Korea and Japan – but in other Western countries as well.

Its application has been utilized further not only as a supplement but it is also being applied for pharmaceuticals, cosmetics and beverages

Ancient Beliefs about Ganoderma

Numerous legends provide a rich and extensive account about Ganoderma lucidum. It was said that in the early days in China, Ganoderma is very rare and hard to obtain. People during the time of the emperors considered it as a treasure greater than any jewel because they believe it provides an incredible source of energy and youthfulness. Furthermore, it was also mentioned that

1. It is the favourite food supplement of the Chinese Royal Family

2. Taoist revered it as "Elixir of Immortality,"

3. The Emperors of the Great Chinese dynasties, including Japanese royalties, drank tea and concoctions of mushrooms for vitality and long life.

4. In the first Chinese Herbal Text (Shennong Pharmacopeia) written about 2,400 years ago, Reishi is classified as a “superior herb,” which was defined as one that “promotes radiant health and long life because of its normalizing action, and (it is also believed) to cause no side effects even when use(d) continuously.” Reishi is traditionally called as “the mushroom of immortality.”

5. The late Hiroshi Hikino, recognized as the world’s authority on the chemistry of Oriental medicinal plants, called Reishi as one of “the most important elixir(s) in the orient.”

6. It also increases intellectual capacity and banishes forgetfulness.

7. Presently in Asia, it ranks parallel to Ginseng in terms of potency.

The Magic Effects of Ganoderma

Ganoderma has always been shrouded with a mysterious curtain for more than a thousand years. People only know 'Ganoderma can keep one young than give one a long life if taken continously, but no one had ever scientifically investigated why it is so effective.

Under the attentive research done by both Chinese and foreign scholars in recent years, and the cooperative analysis and clinical experiments done by hospitals, colleges, and pharmaceutical manufacturers, its extensive efficacy has finally discovered. It is a hemocatharsis, detoxicant, diuretic, liver protector, intestine regulator, cardiotonic, blood pressure adjustor, a cold tonic, antitussive and expectorant, a tranquilizer, an anti-tumor drug.

Important Components of Ganoderma

1. Organic Germanium (Ge): This can increase the oxygen absorbed by the blood up to 1.5 times, can promote metabolism, and prevent tissue degeneration. According to the research of Dr. Kazuhiko Asai, Ganoderma contains 800-2000 p.p.m. of germanium. This is 4-6 more than ginseng.

2. Polysaccharides: These can improve the body's immune system, and eliminate viruses. Japanese pharmaceutical companies have refined it to medical quality and it has been approved by Koseisho Health Department in Japan for insurance medicine.

3. Its bitter taste. It is under constant study by the Japanese medical and pharmaceutical fields. The efficacy is a result of the interrelation of germanium and polysaccharides. Some plants may contain one or the other, but Ganoderma is much more effective. The combination of components is different from other plants and all of the components must be preserved to insure efficiency.

Ganoderma lucidum and its pharmaceutically active compounds

Ganoderma lucidum is a wood-degrading basidiomycete with numerous pharmacological effects. Since the mushroom is very rare in nature, artificial cultivation of fruiting bodies has been known on wood logs and on sawdust in plastic bags or bottles. Biotechnological cultivation of G. lucidum mycelia in bioreactors has also been established, both on solid substrates and in liquid media by submerged cultivation of fungal biomass. The most important pharmacologically active constituents of G. lucidum are triterpenoids and polysaccharides. Triterpenoids have been reported to possess hepatoprotective, anti-hypertensive, hypocholesterolemic and anti-histaminic effects, anti-tumor and anti-engiogenic activity, effects on platelet aggregation and complement inhibition. Polysaccharides, especially beta-d-glucans, have been known to possess anti-tumor effects through immunomodulation and anti-angiogenesis. In addition, polysaccharides have a protective effect against free radicals and reduce cell damage caused by mutagens.

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Ganoderma lucidum spore extract inhibits endothelial and breast cancer cells in vitro.

This study was conducted to investigate the anti-proliferative activities of medicinal mushroom Ganoderma lucidum (Rei-shi or Mannentake). We have identified an alcohol extract from the spore of Ganoderma lucidum that inhibits the in vitro proliferation of human umbilical vein endothelial cells and MDA-MB231 human breast cancer cells. Further fractionation of the alcohol extract revealed that the ethyl acetate fraction inhibited both cell lines in a dose-dependent manner from 2 to 40 micro g/ml. Our results suggest that the alcohol extract from the spore of Ganoderma lucidum may possess potential anti-tumor and anti-angiogenic activities.

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Ganoderma lucidum (Reishi) in cancer treatment

The popular edible mushroom Ganoderma lucidum (Reishi) has been widely used for the general promotion of health and longevity in Asian countries. The dried powder of Ganoderma lucidum was popular as a cancer chemotherapy agent in ancient China. The authors recently demonstrated that Ganoderma lucidum inhibits constitutively active transcription factors nuclear factor kappa B (NF-kappaB) and AP-1, which resulted in the inhibition of expression of urokinase-type plasminogen activator (uPA) and its receptor uPAR. Ganoderma lucidum also suppressed cell adhesion and cell migration of highly invasive breast and prostate cancer cells, suggesting its potency to reduce tumor invasiveness. Thus, Ganoderma lucidum clearly demonstrates anticancer activity in experiments with cancer cells and has possible therapeutic potential as a dietary supplement for an alternative therapy for breast and prostate cancer. However, because of the availability of Ganoderma lucidum from different sources, it is advisable to test its biologic activity.

source

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DXN Health Food Supplement Series

reishi gano
Reishi Gano (RG)

Reishi Gano (RG) is a kind of mushroom essence formulated from Ganoderma lucidum. It contains a wide variety of nutrients such as polysaccharides, adenosine, triterpenoids, protein and fibre.
The applied Ganoderma lucidum is harvested from a 90-day old red mushroom. Comes in capsule and powder forms, daily intake of Reishi Gano (RG) helps in normalizing the entire body functions and maintains the healthy well being.

Packaging size:
- 30, 90 and 360 capsules
- 15g powder/ bottle

Price: RG-30 - PHP 500 pesos
RG-90 - PHP 1,218.00 pesos

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ganocelium
Ganocelium (GL)

Ganocelium® (GL) is produced from a 18-day old mycelium of Ganoderma lucidum. The mycelium is rich in polysaccharides, adenosine, organic germanium, triterpenes, vitamins, minerals and essential fatty acids.

GL is effective in improving the general health of our body. Like RG, Ganocelium® is also available in both capsule and powder forms.

Packaging size:
- 30, 90 and 360 capsules
- 30g powder/ bottle

Price: GL-30 - PHP 500 pesos
GL-90 - PHP 1,218.00 pesos

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spirulina
Spirulina

Spirulina is a type of blue-green algae which is full of life-giving nutrients such as protein, beta carotene, chlorophyll, vitamin B complex, minerals, essential fatty acids and other important nutrients that our body needs.

It is different from other algae because it is easily digested and absorbed by the body. It is also known as one of the best alkaline food, which helps to change weak acidic body condition to a healthy alkaline one.

DXN is the first MLM company in Malaysia to produce Spirulina from the cultivation process to finished goods. DXN Spirulina is naturally cultivated using selected best species. It is cultivated in a clean pond and no pesticides or herbicides are applied. It is available in tablet and capsule forms to suit your needs.

Packaging size:
- 120, 300, 500 and 1500 tablets

Price: 120 tablets - PHP 805.00 pesos
300 tablets - PHP 1,955.00 pesos
1500 tablets - PHP 8,870.00 pesos

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potenzhi
DXN Potenzhi

DXN Potenzhi is a powerful male tonic supplement to revive your passion and vitality. It contains power-packed, highest potency and quality of Eurycoma longifolia Jack (Tongkat Ali) and Butea superba extracts, which are well known to boost up male physical strength. This formulation is further reinforced with seven precious herb extracts which include Ganoderma, Cordyceps, black pepper, celery, green tea, root of lalang and stem of kayu secang. These herbs have been long treasured as an essential tonic to invigorate male performance and regain virility. This unique blend of 9 pure herb extracts is specially formulated combination for its maximum benefits.

 Daily consumption of DXN Potenzhi helps to:
 * improve blood circulation
 * boost up energy level and endurance
* overcome mental fatigue and exhaustion
* strengthen physical performance
DXN Potenzhi is also considered as the ultimate solution in restoring your male vigor. Let your performance soar with Potenzhi!


Packaging size:
- 30 capsules

Price: 30 capsules - PHP 1,050.00 pesos
==========================================bee pollen
DXN Bee Pollen

Bee Pollen has been a highly regarded health food through the years. It is an excellent source of Vitamin B complex, beta carotene, minerals, amino acids, lecithin and enzymes. It is an effective supplement for those who are on diet or fasting. It contains lecithin that helps to break fats in body. Vitamin B complex in Bee Pollen also helps to increase cellular calories burning capacity. It is an instant energy booster that enhances alertness, relieves brain fatigue and improves physical performance. DXN Bee Pollen tablet is made from selected quality Bee Pollen without any chemical additives and preservatives. It is produced by Good Manufacturing Practice (GMP) certified factory which employs advanced technology for rocessing to ensure all nutrients are well preserved. DXN Bee Pollen in tablet form makes it easy to consume anytime and anywhere.


Packaging size:
-120 tablets

Price: 120 tablets - PHP 790.00 pesos
==========================================andro-g
Andro-G

Andrographis paniculata is a traditional herb recognised by herbalists for centuries as a natural remedy for upper respiratory infections, fever, sore throat and flu. It contains andrographolide a bitter compound that contributes therapeutic effects of this herb. Andro - G is made from 100% pure Andrographis paniculata. It helps to reduce excessive body heat due to its cooling and soothing effect.

Packaging size:
-30 and 90 capsules

Price: 30 capsules - PHP 410.00 pesos
90 capsules - PHP 1,160.00 pesos

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roselle
Roselle Tablet

Roselle or its scientific name Hibiscus sabdariffa is a flowering plant used to grow in both tropical and subtropical regions. The swollen red calyces of the plant contain rich amount of vitamin C and minerals such as zinc, calcium and magnesium.

Now, with DXN Roselle tablet, you can grab the natural goodness of Roselle in a convenient way. The exclusive DXN Roselle tablet provides sufficient vitamins C, D, B1 and B2. You will benefit from a wide range of nutrients while enjoying its fabulous taste.

Vitamin C is necessary to keep your immune system strong, promotes healthy gum and beautify your skin complexion.

Packaging size:
- 120 tablets

Price: 120 tablets - PHP 660.00 pesos
====================================================

cordyceps
Cordyceps

Cordyceps sinensis, one of the most valued Chinese medicinal herbs, is found naturally in the highlands of China, Tibet and Nepal. Cordyceps contains various nutrients and active ingredients, which include cordycepic acid, cordycepin, amino acids, glutamic acid, polysaccharides, vitamin B12 among others.

It has been long-treasured as essential tonic to enhance blood circulation, and maintain healthy kidney function and respiratory system.

Technological advances in DXN Research and Development team has successfully led to the production of DXN Cordyceps in two different packagings. It is made from pure and carefully selected species of DXN Cordyceps, which has been organically cultivated under stringent quality control and testing, - from cultivation to finished goods. DXN Cordyceps is now available in tablet and capsule forms for easy consumption and better absorption by our body.

Packaging size:
- 120 tablets

Price: 120 tablets - PHP 2,330.00 pesos

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lion's mane mushroom
Lion´s Mane Mushroom Tablet

Lion´s Mane mushroom has been a very nutritious and essential food in China and Japan for hundreds of years. Contains bioactive substances such as polysaccharides, adenosine, hericenones and erinacines, Lion´s Mane is also known as the "bear´s head" and "monkey head" mushroom that is rich in essential amino acids needed by the body. Lion´s Mane mushroom helps to support a healthy digestive system. It improves indigestion, relieves stomach and duodenal ulcer and chronic gastritis. In addition, Lion's Mane mushroom helps to maintain a healthy nervous system. DXN Lion´s Mane tablet offers you a convenient way to strengthen your body system anytime, anywhere.

Packaging size:
- 120 tablets

Price: 120 tablets - PHP 1,360.00
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